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Enrico Fermi

The physicist who built the first self-sustaining chain reaction, mastered the art of calibrated estimation under radical uncertainty, and asked—over lunch, almost as a joke—the question that still haunts every serious conversation about artificial intelligence: Where is everybody?
Fermi is the patron saint of thinking clearly when you cannot think completely. Forty seconds after the first atomic bomb detonated at Trinity in 1945, while seasoned physicists stood transfixed, Fermi dropped torn scraps of paper into the blast wave, watched how far they blew, and estimated the explosion’s force on the spot—landing within a factor of two on the most consequential measurement of the century, made with paper, in seconds, under conditions of literally unprecedented uncertainty. That discipline—the willingness to reason under radical uncertainty without pretending to certainty or collapsing into paralysis—is the cognitive skill the AI age most demands and most threatens to erode. On 2 December 1942, in a converted squash court beneath Stagg Field, Fermi watched Chicago Pile-1 go critical—the first self-sustaining criticality event in human history—making him the closest historical analogue we have to the question of intelligence “takeoff.” And then, in 1950, over a casual lunch at Los Alamos, he asked the
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